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Human Atlas of Neonatal Development and Early Life-Immunity (HANDEL-I)

Human Atlas of Neonatal Development and Early Life-Immunity (HANDEL-I) The early life events that influence immune system development have implications in the development of a multitude of diseases including type 1 diabetes (T1D). The immune system is actively evolving and integrating dynamic signals from the host’s environment, not only to ward off external infection but…

Helmsley Grant to UFDI to Study Immune Repertoire in T1D

University of Florida and Kings College London have secured a $3.7 million grant funded by Adaptive Biotechnologies and the Leona M. and Harry B. Helmsley Charitable Trust to profile T cell receptor sequences in Type 1 Diabetes. Congratulations to co-investigators Dr. Todd Brusko and Dr. Mark Peakman!

Join Our Mission

The Brusko Lab is currently recruiting a Postdoc to work on our NIH R01 “The CD226 and TIGIT Costimulatory Axis in Type 1 Diabetes.”

ATG Preserves β-Cell Function in Clinical Trial

The 1-year C-peptide was significantly higher (β-cell preservation) in subjects treated with ATG versus placebo (P = 0.0003) but not in those treated with ATG/GCSF versus placebo (P = 0.031).

What’s your GRS?

The Brusko Lab and collaborators are trying to better understand how genes influence T1D risk

Our Research Focus

Our laboratory aims to harness the power of naturally occurring regulatory T cells to correct unwanted immune responses that deliver a cure for type 1 diabetes.

Our Staff

From undergraduate students to post-doctoral fellows – every set of hands is important.

Our Publications

View how Dr. Brusko’s research has progressed and see where our research currently stands.

Our Space

The Brusko Lab enjoys being a part of UFHealth and the UF Diabetes Institute in Gainesville, Florida.