Diabetes
Treg-Specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T-Cell Stability
Diabetes. 2023 Nov 1;72(11):1629-1640. doi: 10.2337/db23-0307. PMID: 37625150; PMCID: PMC10588280.
Authors:
Thirawatananond P, Brown ME, Sachs LK, Arnoletti JM, Yeh WI, Posgai AL, Shapiro MR, Chen YG, Brusko TM.
J Immunol
Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells
J Immunol. 2023 Oct 1;211(7):1108-1122. doi: 10.4049/jimmunol.2200651. PMID: 37594278; PMCID: PMC10511790.
Authors:
Shapiro MR, Peters LD, Brown ME, Cabello-Kindelan C, Posgai AL, Bayer AL, Brusko TM.
JCI INSIGHT
Human immune phenotyping reveals accelerated aging in type 1 diabetes
JCI Insight. 2023 Sep 8;8(17):e170767. doi: 10.1172/jci.insight.170767. PMID: 37498686; PMCID: PMC10544250.
Authors:
Shapiro MR, Dong X, Perry DJ, McNichols JM, Thirawatananond P, Posgai AL, Peters LD, Motwani K, Musca RS, Muir A, Concannon P, Jacobsen LM, Mathews CE, Wasserfall CH, Haller MJ, Schatz DA, Atkinson MA, Brusko MA, Bacher R, Brusko TM.
JCI INSIGHT
Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes
JCI Insight. 2023 Aug 22;8(16):e161812. doi: 10.1172/jci.insight.161812. PMID: 37432736; PMCID: PMC10543726.
Authors:
Jacobsen LM, Diggins K, Blanchfield L, McNichols J, Perry DJ, Brant J, Dong X, Bacher R, Gersuk VH, Schatz DA, Atkinson MA, Mathews CE, Haller MJ, Long SA, Linsley PS, Brusko TM.
Front Immunol
Modeling cell-mediated immunity in human type 1 diabetes by engineering autoreactive CD8+ T cells
Front Immunol. 2023 May 30;14:1142648. doi: 10.3389/fimmu.2023.1142648. PMID: 37325626; PMCID: PMC10262917.
Authors:
Peters LD, Yeh WI, Arnoletti JM, Brown ME, Posgai AL, Mathews CE, Brusko TM.
Sci Data
A genomic data archive from the Network for Pancreatic Organ donors with Diabetes
Sci Data. 2023 May 26;10(1):323. doi: 10.1038/s41597-023-02244-6. PMID: 37237059; PMCID: PMC10219990.
Authors:
Perry DJ, Shapiro MR, Chamberlain SW, Kusmartseva I, Chamala S, Balzano-Nogueira L, Yang M, Brant JO, Brusko M, Williams MD, McGrail KM, McNichols J, Peters LD, Posgai AL, Kaddis JS, Mathews CE, Wasserfall CH, Webb-Robertson BM, Campbell-Thompson M, Schatz D, Evans-Molina C, Pugliese A, Concannon P, Anderson MS, German MS, Chamberlain CE, Atkinson MA, Brusko TM.
J Biomed Mater Res A
Biomaterials-based nanoparticles conjugated to regulatory T cells provide a modular system for localized delivery of pharmacotherapeutic agents
J Biomed Mater Res A. 2023 Feb;111(2):185-197. doi: 10.1002/jbm.a.37442. Epub 2022 Sep 9. PMID: 36082558; PMCID: PMC9742177.
Authors:
Marshall GP, Cserny J, Wang CW, Looney B, Posgai AL, Bacher R, Keselowsky B, Brusko TM.