Lindsey Sachs is a recent graduate of the University of Florida (Spring 2022) with a Bachelors of Science in Microbiology with a minor in Health Disparities in Society. Lindsey joined the Brusko Lab in the Spring of 2021 as an undergraduate volunteer investigating the therapeutic potential of modulating the CD226/TIGIT costimulatory pathway for the development of therapeutics to treat Type 1 Diabetes. As a lab technician, Lindsey currently assists with flow cytometry and mouse model experiments as well as day to day laboratory maintenance and care.
- Brown ME, Peters LD, Hanbali SR, Arnoletti JM, Sachs LK, Nguyen KQ, Carpenter EB, Seay HR, Fuhrman CA, Posgai AL, Shapiro MR, and Brusko TM (2022) Human CD4+CD25+CD226– Tregs Demonstrate Increased Purity, Lineage Stability, and Suppressive Capacity Versus CD4+CD25+CD127lo/- Tregs for Adoptive Cell Therapy. Front. Immunol. 13:873560. doi: 10.3389/fimmu.2022.873560
Abstracts & Presentations
- Arnoletti JM, Peters LD, Musca R, Sachs LK, Nguyen KQ, Meckler MP, Brusko TM. Effects of CRISPR/Cas9 mediated T Cell Receptor Knockout in Lentiviral Transduced CD4+ T cells to Improve Immunotherapies for Type 1 Diabetes. Poster Presented at: 2022 UF College of Medicine Research Day; 2022 Apr 4; Gainesville, FL.
- Brown ME, Arnoletti JM, Sachs LK, Nguyen KQ, Lee JJ, Brusko TM. CD226– Human Regulatory T Cells Exhibit Increased Stability Compared to Conventionally Sorted Populations. Poster presented at: 18th Congress of the Immunology of Diabetes Society (IDS); 2021 Nov 1-4; Virtual. (Outstanding Abstract Award Received)
Lab: (352) 273-9300