THE URGENCY OF NOW

The peak age for being diagnosed with type 1 diabetes is around 13 or 14 years, but people can be diagnosed when they are much younger (including babies) and older (even over 40). Type 1 diabetes requires your attention every day. The mission of our lab is to make transformative discoveries to work toward diabetes-free world. Work in the Brusko lab is funded by NIH , The Leona M. and Harry B. Helmsley Charitable Trust, and the Network for Pancreatic Organ donors with Diabetes, and JDRF.

Lab news

HIRN EMERGING LEADERS INVESTIGATORS

Robert Sharp, PhD
University of Florida
Consortium: CHIB
Project: The SIRP:CD47 Signaling
Pathway in Pancreatic b-Cell Survival

HIRN 2021 news letter

IDS 2021 (Nov. 1 2021 – Nov, 4, 2021)

IDS 2021 Outstanding Abstract Awardees: Leeana Peters, Matthew Brown

Leeana Peters
Abstract Title
Single cell transcriptomic and epigenetic analysis of pancreatic lymph node tissues in T1D

Matthew Brown
Abstract Title
CD226- Human Regulatory T Cells Exhibit Increased Lineage Stability Compared to Conventionally Sorted Populations

Recent publications

Frontiers in Immunology

The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes
REVIEW article
Front. Immunol., 16 September 2021 | https://doi.org/10.3389/fimmu.2021.739048

Authors: Robert C Sharp, PhD, Matthew E Brown Melanie R Shapiro, PhD, Amanda L Posgai, PhD, Todd M Brusko, PhD.
PMID: 34603322; PMCID: PMC8481641

Robert's review on Frontiers

New “Pancreatic Islet on a Chip” System Will…

Category: Feature

University of Florida researchers will use a new $5 million grant to develop a “pancreatic islet on a chip” — a platform that will allow them…

Islet on a Chip

Human Atlas of Neonatal Development and Early…

Category: Feature

Human Atlas of Neonatal Development and Early Life-Immunity (HANDEL-I) The early life events that influence immune system development have…

HANDEL-I

Helmsley Grant to UFDI to Study Immune Repertoire…

Category: Feature

University of Florida and Kings College London have secured a $3.7 million grant funded by Adaptive Biotechnologies and the Leona M. and Harry B…

DNA

T1D news

August 29, 2019

Pancreas on a chip

Beta-cell transplantation

pancreas on a chip

International Clinical Centers

Type 1 Diabetes TrialNet

The University of Florida (UF) is one of twenty-five Type 1 Diabetes TrialNet International Clinical Centers at the forefront of type 1 diabetes research. Led by Desmond Schatz, MD, the TrialNet team at UF is dedicated to preventing type 1 diabetes and stopping disease progression by preserving insulin production before and after diagnosis.

Biomedical Sciences Building