Matthew Brown is a second-year undergraduate student at UF majoring in biochemistry. He joined the Brusko Lab in the summer of 2019 to study the autoimmune response involving the destruction of pancreatic beta-cells which leads to Type 1 Diabetes (T1D). Matthew is currently working with Dr. Robert Sharp to investigate the effects of intracellular signaling between two transmembrane proteins (CD47 & SIRPγ) to determine whether interruptions within this signaling pathway could play a role in T1D pathogenesis. Matthew is also researching the therapeutic potential of CD226 & TIGIT to evaluate the possibility of developing an adoptive Treg cell therapy which modifies this particular costimulatory axis.
- UF Center for Undergraduate Research – 2020 Emerging Scholar
- UF College of Medicine – 2020 University Scholar
Lab: (352) 273-9300