Matthew Brown
Undergraduate Researcher

Matthew Brown 12-18-19
Matthew Brown is a third-year undergraduate student at UF majoring in biochemistry & molecular biology. He joined the Brusko Lab in the summer of 2019 to study the autoimmune response involving the destruction of pancreatic beta-cells which leads to Type 1 Diabetes (T1D). Matthew is researching the therapeutic potential of modulating the CD226 & TIGIT costimulatory pathway to develop a more efficient adoptive Treg cell therapy as well as monoclonal antibody therapeutic approaches. Matthew is also currently working with Dr. Robert Sharp to investigate the effects of intracellular signaling between two transmembrane proteins (CD47 & SIRPγ) to determine whether interruptions of this signaling pathway play a role in T1D pathogenesis. 


Abstracts & Presentations

Fellowships & Awards

  • UF Center for Undergraduate Research – 2020 Emerging Scholar
  • UF College of Medicine – 2020 University Scholar
  • UF College of Medicine – 2021 University Scholar


Lab: (352) 273-9300